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Acute Lethality Prediction And Sar Model
Prediction of Acute Mammalian Toxicity Using QSAR Methods: A Case Study of Sulfur Mustard and Its Breakdown Products. Patricia Ruiz 1,* , Gino ... In this manuscript we investigate using the lethal dose that kills fifty percent of a test population (the LD50) for determining relative toxicity of a number of substances. In general, the ... in the field. Keywords: sulfur mustard; QSAR; SAR; mammalian oral; LD50; quantitative structure-activity relationship; in silico modeling& ...
acute lethality prediction and sar model
Here, we used a mouse model of acute pancreatitis–associated (AP-associated) ALI to determine the role of IL-6 in ALI lethality. Il6-deficient mice had a lower death rate compared with wild-type mice with AP, while mice& ...
The outbreak of severe acute respiratory syndrome (SARS) was one of the more serious recent pandemics. It was caused by a member of the coronavirus ... Since the mid-1990s, bats have been recognised as an important source of many emerging viruses that can cause severe or lethal disease in people and livestock. These include the Hendra, Nipah, Ebola, ... What we could not predict was when or where it would happen. But this was addressed by the MERS& ...
The genome, which is just over 30 KB, contains at least 10 predicted open reading frames (ORFs) [4]. The genome size, organization and sequence analysis revealed that the NCoV is most ... With a mortality of approximately 11% seen with SARS-CoV infection, the identification of NCoV from patients with similar acute respiratory illness as with SARS-CoV is of a real concern. Coronaviruses are a large family of enveloped, single-stranded RNA viruses that infect a& ...
Prediction of Acute Mammalian Toxicity Using QSAR Methods: A Case Study of Sulfur Mustard and Its Breakdown Products. Patricia Ruiz 1,* , Gino ... In this manuscript we investigate using the lethal dose that kills fifty percent of a test population (the LD50) for determining relative toxicity of a number of substances. In general, the ... in the field. Keywords: sulfur mustard; QSAR; SAR; mammalian oral; LD50; quantitative structure-activity relationship; in silico modeling& ...
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